Phyllanthus – Hepatitis B, and more

by | Diabetes, Hepatitis, Menstrual Discomfort, Skin Ulcers, Sores

Phyllanthus has been used in Ayurvedic medicine for over 2,000 years and has a wide number of traditional uses including internal use for jaundice, gonorrhea, frequent menstruation, and diabetes and topical use as a poultice for skin ulcers, sores, swelling, and itchiness.

The young shoots of the plant are administered in the form of an infusion for the treatment of chronic dysentery.

Phyllanthus: Common names: Bahupatra, Bhuiamla. Botanical name: Phyllanthus niruri. Phyllanthus is an herb found in central and southern India. It can grow from 30–60 centimeters in height and blooms with many yellow flowers. Phyllanthus species are also found in other countries, including China (e.g., Phyllanthus urinaria), the Philippines, Cuba, Nigeria, and Guam. All parts of the plant are used medicinally to treat hepatitis and pain .

Active constituents: Phyllanthus primarily contains lignans (e.g., phyllanthine and hypophyllanthine), alkaloids, and flavonoids (e.g., quercetin).

Phyllanthus blocks DNA polymerase, the enzyme needed for the hepatitis B virus to reproduce. In one study, 59% of those infected with chronic viral hepatitis B lost one of the major blood markers of HBV infection (e.g., hepatitis B surface antigen) after using 900 mg of phyllanthus per day for 30 days. While clinical trials on the effectiveness of phyllanthus for HBV have been mixed, the species P. urinaria and P. niruri seem to work better than P. amarus.

Clinical trials with hepatitis B patients have used 900–2,700 mg of phyllanthus per day.

Research has used the powdered form of phyllanthus ranging from 900–2,700 mg per day for three months. No side effects have been reported using phyllanthus as recommended in the amounts above. At the time of writing, there were no well-known drug interactions with phyllanthus.

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